With suicides on the rise , the U.S. government wants to make the national crisis hotline easier to reach. Once implemented, people will just need to dial 988 to seek help. Currently, the National Suicide Prevention Lifeline uses a 10-digit number, 800-273-TALK (8255). Callers are routed to one of 163 crisis centers, where counselors answered
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(HealthDay)—The economic burden of disease progression is considerable among multiple myeloma (MM) patients receiving drug therapy across all lines of therapy (LOTs), according to a study published online Aug. 7 in Leukemia & Lymphoma. May Hagiwara, Ph.D., from Policy Analysis Inc. in Brookline, Massachusetts, and colleagues used data from a large U.S. claims database to
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Five years ago, David C. Fajgenbaum, MD, MBA, MSc, both a Penn Medicine researcher and patient, tried an experimental treatment on himself based on his laboratory research findings in the hopes of saving his own life. He has been in remission ever since. Now his research is shedding new light on why it worked, paving
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A new study analyzing samples from patients with and without acute flaccid myelitis (AFM) provides additional evidence for an association between the rare but often serious condition that causes muscle weakness and paralysis, and infection with non-polio enteroviruses. The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, funded
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Physical manifestations of negative memories in the hippocampus could underlie cognitive symptoms of depression, according to research in mice published in JNeurosci. Inhibiting these manifestations could be a future treatment route. Groups of neurons that are activated after an experience are thought to be the physical representation of memory. These so-called engrams in the hippocampus
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Hyperactive neurons in specific areas of the brain are believed to be an early perturbation in Alzheimer’s disease. For the first time, a team from the Technical University of Munich (TUM) was able to explain the reasons and mechanisms underlying this early and therefore important neuronal dysfunction. They found that the excitatory neurotransmitter glutamate persists
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The Lion King is a movie about a young lion cub named Simba, who idolizes his father, King Mufasa, and is eager for his own royal destiny. Scar, former heir to the throne before Simba’s birth, sends Mufasa to his death and convinces Simba that the king’s death is the young cub’s own fault. For
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Researchers identified a gene in fruit flies that helps prevent the hyperexcitability of specific neurons that trigger seizures. In humans, mutations in the gene may be linked to seizures associated with Long QT Syndrome. A research team led by Yehuda Ben-Shahar of Washington University in St. Louis report these findings in a paper published 8th
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You’ve lost count of the sleepless nights spent in a hospital, but now your loved one is finally ready to go home following a stroke. Are you prepared to care for them? If you are like most people, you may know how to spot a stroke, but you don’t know the first thing about what
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Researchers from the UCLA School of Dentistry have provided insight into how the mechanical process of bone loss works and have also identified a protein that is responsible for recycling of the cells that can also promote bone loss. The team showed that by eliminating a key protein responsible for the activation of bone loss,
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